Aescin (Aescin)
Overview of Aescin
Aescin is an active principle of Aesculus. Aescin is used for the prevention and treatment of various peripheral disorders including haemorrhoids and post-operative oedema.
Indication of Aescin
Aescin is primarily indicated in conditions like Hemorrhoids, Musculoskeletal disorders, Pain, Peripheral vascular disease, Post operative oedema, Rheumatoid arthritis, and can also be given in adjunctive therapy as an alternative drug of choice in Diarrhoea.
Contraindication of Aescin
Aescin is contraindicated in conditions like Renal impairment.
Side Effects of Aescin
Aescin produces potentially life-threatening effects which include Renal failure, Anaphylaxis. which are responsible for the discontinuation of Aescin therapy.,The signs and symptoms that are produced after the acute overdosage of Aescin include Vomiting, Diarrhea, Dilated pupils, Lack of coordination, Paralysis, Muscle twitching.
Precautions of Aescin
Acute renal failure has been reported in patients given higher doses, sometimes in conjunction with other nephrotoxic drugs.