Vinblastine sulphate (Vinblastine sulphate)
Overview of Vinblastine sulphate
Vinblastine is an antineoplastic (anticancer) agent. Vinblastine (Sulphate) is alkaloid derivative of Vinca rosea, the periwinkle plant. Vinblastine (Sulphate) is a parenteral, cell cycle-phase specific antineoplastic agent used in the management of breast carcinoma, bladder carcinoma, Hodgkin's disease, melanoma, and testicular carcinoma. Vinblastine is similar to vincristine in action, but their toxicities differ significantly. Vinblastine was approved by the FDA in 1961. Vinblastine (Sulphate) is used in combination of different anticancer drugs to obtain best therapeutic effect and to minimize side effects or toxicity.
Indication of Vinblastine sulphate
Vinblastine Sulphate is primarily indicated in conditions like Acute leukemia, Histiocytosis, Hodgkin's disease, Kaposis sarcoma, Lymphomas, Non-hodgkin's lymphoma, NSAID-associated ulceration, Solid tumor, Testicular cancer.
Contraindication of Vinblastine sulphate
No data regarding the contra indications of Vinblastine (Sulphate) is available.
Side Effects of Vinblastine sulphate
The severe or irreversible adverse effects of Vinblastine (Sulphate), which give rise to further complications include GI symptoms.,Vinblastine (Sulphate) produces potentially life-threatening effects which include Myelosuppression. which are responsible for the discontinuation of Vinblastine (Sulphate) therapy.,The signs and symptoms that are produced after the acute overdosage of Vinblastine (Sulphate) include Myelosuppression, Neurotoxicity.,The symptomatic adverse reactions produced by Vinblastine (Sulphate) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Vomiting, Diarrhea, Abdominal cramps, Constipation, Paralytic ileus.
Precautions of Vinblastine sulphate
Vinblastin can lower body's ability to fight an infection, consult the doctor if any signs of an infection such as fever, sore throat, rash or chills appear. Avoid contact with people with the flu. Do not have immunizations or vaccinations without consent of doctor and avoid contact with people who have recently received oral polio vaccine. Contraceptive (birth control) measures are recommended for use in men and women while taking this medication. It is not recommended for use in pregnant or nursing women. Avoid aspirin, alcohol and citrus juices.