Pimozide (Pimozide)
Overview of Pimozide
Pimozide is a long-acting antipsychotic with general properties similar to that of chlorpromazine. Pimozide is used in psychotic disorder specially in schizophrenia, paranoid states and Tourette`s syndrome. Pimozide is also used to control nausea, vomitting and intractable hiccups.
Indication of Pimozide
Pimozide is primarily indicated in conditions like Delusional disorder, Erotomania, Gille de la tourette syndrome, Mania, Psychosis, Schizophrenia.
Contraindication of Pimozide
Pimozide is contraindicated in conditions like Cardiac arrhythmia,Depression,Parkinsonism,CNS depression,Ecg abnormalities.
Side Effects of Pimozide
The severe or irreversible adverse effects of Pimozide, which give rise to further complications include Tardive dyskinesia.,Pimozide produces potentially life-threatening effects which include Coma, Muscle rigidity, Agranulocytosis, Neuroleptic Malignant Syndrome, Unconsciousness. which are responsible for the discontinuation of Pimozide therapy.,The symptomatic adverse reactions produced by Pimozide are more or less tolerable and if they become severe, they can be treated symptomatically, these include Tiredness, Anorexia, Insomnia, Acute dystonia, Gynecomastia, Galactorrhea, Extrapyramidal effects, HyperprolactinemiaX, Oligomenorrhea, Amenorrhea, Pseudoparkinsonism, Rigidity, Akinesia.
Precautions of Pimozide
Patients should be observed caution while driving or performing other tasks requiring alertness, because it may produced drowsiness or blurred vision. Pimozide should be used with caution in patients with kidney or liver diseases. Correct potassium insufficiency and diarrhea before initiating therapy. It should be used with caution in patients whose condition may be aggravated by anticholinergic activity.