Pinacidil Monohydrate (Pinacidil Monohydrate)
Overview of Pinacidil Monohydrate
Pinacidil Monohydrate is potassium channel opener. It is used in the managemnet of hypertension. It produces direct vasodilatation of the arterioles and reduces the blood pressure, and peripheral resistance but causes fluid retension.
Indication of Pinacidil Monohydrate
Pinacidil Monohydrate is primarily indicated in conditions like Bladder hyperactivity, Hypertension, Impotency, Renal hypertension.
Contraindication of Pinacidil Monohydrate
Pinacidil Monohydrate is contraindicated in conditions like Cardiac arrhythmia,Ischaemic heart disease,Cerebrovascular disease.
Side Effects of Pinacidil Monohydrate
The severe or irreversible adverse effects of Pinacidil Monohydrate, which give rise to further complications include Tachycardia, Palpitation, Oedema.,The symptomatic adverse reactions produced by Pinacidil Monohydrate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Nausea, Palpitation, Tachycardia, Rashes, Increased intracranial pressure.
Precautions of Pinacidil Monohydrate
Pinacidil monohydrate should be used with caution in patients with symptomatic ischaemic heart disease, cerebrovascular insufficiency, renal or hepatic (liver) dysfunction or pre-existing tachyarrhythmias.