Nifedipine (Nifedipine)
Overview of Nifedipine
It is of Synthetic origin and belongs to Pyridine. It belongs to Calcium L-channel antagonist pharmacological group on the basis of mechanism of action. The Molecular Weight of Nifedipine is 346.30.
Indication of Nifedipine
Indications
Contraindication of Nifedipine
Nifedipine is contraindicated in conditions like Diabetes mellitus,Cardiac insufficiency,Hypotension.
Side Effects of Nifedipine
The severe or irreversible adverse effects of Nifedipine, which give rise to further complications include Flushing, Dizziness, Exacerbated angina.,Nifedipine produces potentially life-threatening effects which include Cardiovascular collapse. which are responsible for the discontinuation of Nifedipine therapy.,The signs and symptoms that are produced after the acute overdosage of Nifedipine include Bradycardia, Hypotension, Unconsciousness.,The symptomatic adverse reactions produced by Nifedipine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Palpitation, GI upset, Ankle swelling, Paresthesias, Reversible Gingival HyperplasiaX.
Precautions of Nifedipine
Nifidipine should be used with caution in patients with kidney or liver disease. Consider decrease in dose of calcium channel blockers & monitor drug response in cirrhosis patients.