Metoclopramide Hcl (Metoclopramide Hcl)
Overview of Metoclopramide Hcl
Metoclopramide Hcl is antiemetic with dopamine antagonist action in brain and peripheral effect on gastro-intestinal tract where it stimulates motility to improve gastric emptying and intestinal transit. Metoclopramide Hcl is used to treat nausea, and vomiting of most causesand as an adjunct to X-ray examination of the gut. Metoclopramide Hcl is given both orally and parentrally.
Indication of Metoclopramide Hcl
Metoclopramide Hcl is primarily indicated in conditions like Delayed gastric emptying, Diagnostic procedures, Flatulence, Gastritis, GI motality disorder, Heart burn, Hiccup in palliative care, Migraine, Nausea and vomiting, Nausea and vomiting (chemotherapy induced), Reflux oesophagitis, and can also be given in adjunctive therapy as an alternative drug of choice in Defective lactation, Hiccup due to gastric distension in palliative care, Postural hypotension, Psychosis.
Contraindication of Metoclopramide Hcl
Metoclopramide (HCl) is contraindicated in conditions like Parkinsonism,Phaeochromocytoma,Dystonia,Pyloric stenosis.
Side Effects of Metoclopramide Hcl
The severe or irreversible adverse effects of Metoclopramide (HCl), which give rise to further complications include Tardive dyskinesia, Parkinsonism, Acute dystonia, Acute porphyria, Acute dyskinesia, Extrapyramidal reactions.,The signs and symptoms that are produced after the acute overdosage of Metoclopramide (HCl) include Tachycardia, Drowsiness, Drowsiness, Dystonia.,The symptomatic adverse reactions produced by Metoclopramide (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Drowsiness, Diarrhea, Akathisia, Skin rash, Impotence, Hypotension, Gynecomastia, Galactorrhea, Hypertension, Increase in heart rate, Hyperprolactinemia, Mental disturbances, neuroleptic disorder.
Precautions of Metoclopramide Hcl
Patient should observe caution while driving or performing other tasks requiring alertness because it may produce drowsiness. Metoclopramide should be used with caution in patients with previously detected breast cancer.Children, Young adults & elderly should be treated with care as they are at increased risk of extrapyramidal reactions. Care should be taken when metoclopramide is given to pateints with renal or hepatic impairment.