Antilymphocyte Immune Globulin (Antilymphocyte Immune Globulin)
Overview of Antilymphocyte Immune Globulin
Antilymphocyte Immune Globulin may be added in immunosuppressant regimens in organ transplantation patient to treat acute rejection episode, Antilymphocyte Immune Globulin is also used in the treatment of aplastic anemia in patients unsuitable for bone marrow transplantation.
Indication of Antilymphocyte Immune Globulin
Antilymphocyte Immune Globulin is primarily indicated in conditions like Aplastic anemia, Bone marrow depletion of t cells, Rejection crises of transplanted organs.
Contraindication of Antilymphocyte Immune Globulin
Antilymphocyte Immune Globulin is contraindicated in conditions like Allergy,Thrombocytopenia,Seizures,Parasite infection.
Side Effects of Antilymphocyte Immune Globulin
The severe or irreversible adverse effects of Antilymphocyte Immune Globulin, which give rise to further complications include Tachycardia, Hypotension, Febrile reactions.,Antilymphocyte Immune Globulin produces potentially life-threatening effects which include Anaphylactoid reactions, Thrombocytopenia, Serum sickness. which are responsible for the discontinuation of Antilymphocyte Immune Globulin therapy.,The symptomatic adverse reactions produced by Antilymphocyte Immune Globulin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Pruritus, Local thrombophlebitis, Erythema.
Precautions of Antilymphocyte Immune Globulin
Antilymphocyte is not recommended for use during pregnancy or lactation. Immunosuppressant drug should not be given, where possible, to patients with acute infection, dosage reduction or withdrawal should be considered if infection develops, until the infection has been controlled. Blood counts and measurement of hemoglobin concentration should be carried out routinely, it help to predict the onset of bone marrow depression. It must be handled with great care and avoid contact with skin and eyes and should not be inhaled.