Anistreplase (Anistreplase)
Overview of Anistreplase
Anistreplase is a thrombolytic drug. It consists of a complex of purified human plasminogen and becterial streptokinase that has been acylated to protect the active site of the enzyme. It prevents blood from clotting. Anistreplase is used in the treatment of deep vein thrombosis and pulmonary embolism. Anistreplase is effective in reducing the risk of death following an acute heart attack.it may produce allergic recatuions.
Indication of Anistreplase
Anistreplase is primarily indicated in conditions like Myocardial infarction.
Contraindication of Anistreplase
Anistreplase is contraindicated in conditions like Hypertension,Peptic ulcer,Cardiac stroke,Vaginal bleeding,Chest compresion,Intracranial neoplasm,Diabetic retinopathy,Hemorrhagic diathesis.
Side Effects of Anistreplase
The severe or irreversible adverse effects of Anistreplase, which give rise to further complications include Allergic reactions.,Anistreplase produces potentially life-threatening effects which include Bleeding. which are responsible for the discontinuation of Anistreplase therapy.,The signs and symptoms that are produced after the acute overdosage of Anistreplase include Hemorrhage.,The symptomatic adverse reactions produced by Anistreplase are more or less tolerable and if they become severe, they can be treated symptomatically, these include Mild flushing, Shaking, Tight breathing.
Precautions of Anistreplase
Anistreplase should be used with caution in patients with bleeding, blood vessel abnormalities, brain tumor, history of stroke, recent surgery, extremely high blood pressure (200/120 or higher). This drug should be used with caution when the following conditions exist: child birth with in 10days, blood-clotting problems, retinal bleeding (recent) gastrointestinal or urinary tract bleeding (recent), ulcer, recent invasive medical procedure or any heart abnormalities.