Etodolac (Etodolac)
Overview of Etodolac
Etodolac is a newer pyranoindole acetic acid derivative. Etodolac is NSAID (non-steroidal anti-inflammatory drug). It relieves pain and reduces fever and inflammation. Etodolac is a racemic mixture of R and S forms, the R form being inactive. itused to treat pain, swelling and stiffness associated with arthritis.
Indication of Etodolac
Etodolac is primarily indicated in conditions like Endometrial thinning before intra-uterine surgery, Osteoarthritis, Pain and inflammation in rheumatoid arthritis, Rheumatoid arthritis.
Contraindication of Etodolac
Etodolac is contraindicated in conditions like Peptic ulcer,GI hemorrhage.
Side Effects of Etodolac
The severe or irreversible adverse effects of Etodolac, which give rise to further complications include Thrombocytopenia, Leucopenia.,Etodolac produces potentially life-threatening effects which include Gastrointestinal hemorrhage. which are responsible for the discontinuation of Etodolac therapy.,The signs and symptoms that are produced after the acute overdosage of Etodolac include Upper gastrointestinal irritation.,The symptomatic adverse reactions produced by Etodolac are more or less tolerable and if they become severe, they can be treated symptomatically, these include Indigestion, Photosensitivity reactions.
Precautions of Etodolac
Etodolac should be used with caution in patients with liver or kidney disease, blood disorders, ulcers, heart disease, alcohol use, high blood pressure, eye disease or allergy, especially drug allergy. It should be used with caution when performing tasks requiring alertness. Limit alcohol intake as it may intensify the drowsiness effect of this medication and make stomach or intestines more likely to bleed. Do not take aspirin without consulting the doctor. Caution is advised when this drug is used in the elderly patients. This medication should be used during pregnancy or lactation only if clearly needed. The use of this drug in the last 6 months of pregnancy is not recommended.