Etomidate (Etomidate)
Overview of Etomidate
Etomidate is a sedative, hypnotic. Administered intravenously. Etomidate is a carboxylated imidazole. Etomidate is anesthetic agent.
Indication of Etomidate
Etomidate is primarily indicated in conditions like Anaesthesia induction in cardiovascular patients.
Contraindication of Etomidate
Etomidate is contraindicated in conditions like Epilepsy,Porphyrias,Adrenocortical insufficiency.
Side Effects of Etomidate
The severe or irreversible adverse effects of Etomidate, which give rise to further complications include Cortisol synthesis inhibition.,Etomidate produces potentially life-threatening effects which include Reduction in serum cortisol. which are responsible for the discontinuation of Etomidate therapy.,The signs and symptoms that are produced after the acute overdosage of Etomidate include Rapid fall in BP.,The symptomatic adverse reactions produced by Etomidate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Vomiting, Involuntry muscle movements, Pain at injection site.
Precautions of Etomidate
Patients should observe caution while driving or performing other tasks requiring alertness, because may cause drowsiness. Patients with chronic disease such as diabetes or hypertension may require adjustment to their therapy before anesthesia. Anesthetics should be given with caution in patients with cardiac, respiratory, renal or hepatic impairment.