Dimercaprol (Dimercaprol)
Overview of Dimercaprol
Dimercaprol is a metal complexing agent, used as antidote to poisoninig by arsenic, mercury, lead and sometimes other metals, administered orally.
Indication of Dimercaprol
Dimercaprol is primarily indicated in conditions like Acute dichloroarsine poisoning, Antimony poisoning, Arsenic poisoning, Lead poisoning, Superficial lesions from heavy metals, Wilson's disease.
Contraindication of Dimercaprol
Dimercaprol is contraindicated in conditions like Hypertension,Hepatic failure,Iron poisoning,Selenium poisoning,Tellurium poisoning,Cadmium poisoning,Organic mercury poisoning.
Side Effects of Dimercaprol
The severe or irreversible adverse effects of Dimercaprol, which give rise to further complications include Anemia, Anemia, Anemia, Anemia.,Dimercaprol produces potentially life-threatening effects which include Exacerbation of hypertension, Exacerbation of hypertension, Iron toxicity potentiation. which are responsible for the discontinuation of Dimercaprol therapy.,The symptomatic adverse reactions produced by Dimercaprol are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Nausea, Vomiting, Fever, Tachycardia, Abdominal pain, Sweating, Local pain, Increased BP, Tingling of the hand, Lacrimation, Pain at injection site, Lip burning sensation, Mouth burning sensation, Pain at injection site.
Precautions of Dimercaprol
Dimercaprol should be used with caution in patients with hypertension or impaired renal function. It should be discontinued or use with extreme caution if acute renal insufficiency develops during treatment. Alkalinization of the urine may protect the kidney during therapy. Dimercaprol should not be given to patients with impaired hepatic function unless due to arsenic poisoning. It should not be used in the treatment of poisoning due to cadmium, iron or selenium because the dimercaprol-metal complexes formed are more toxic than the metal themselves.