Dinoprost (Dinoprost)
Overview of Dinoprost
Dinoprost is a natural oxytocic protaglandin. Dinoprost is a synthetic derivative of itone in which the O atom in 9-position of the latter is reduced to OH. Dinoprost is effective as an abortifacient i.e., causing abortion.
Indication of Dinoprost
Dinoprost is primarily indicated in conditions like Abortion, Haemorrhage, Hydatidiform mole, Labor induction.
Contraindication of Dinoprost
Dinoprost is contraindicated in conditions like Asthma,Glucoma,Pelvic infections.
Side Effects of Dinoprost
The severe or irreversible adverse effects of Dinoprost, which give rise to further complications include Intravascular coagulation.,Dinoprost produces potentially life-threatening effects which include Cardiogenic collapse. which are responsible for the discontinuation of Dinoprost therapy.,The signs and symptoms that are produced after the acute overdosage of Dinoprost include Collapse, Severe GI symptoms.,The symptomatic adverse reactions produced by Dinoprost are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Nausea, Vomiting, Diarrhea, Flushing, Pyrexia, Bronchospasm, Shivering, Wheezing, dizziness, bronchoconstriction.
Precautions of Dinoprost
Dinoprost should be used with caution in patients with medical history, including any allergy (especially drug allergy), pelvic infections, heart, lungs, kidney or liver diseases, asthma, high or low blood pressure, anemia, diabetes, seizure disorder, infections in the vaginal area. This medication should be used only when clearly needed during pregnancy or lactation.