Bovine Insulin (Bovine Insulin)
Overview of Bovine Insulin
Insulin is a hormone produced by the beta cells of the islets of langerhans of the pancres and consists of 2 chains of aminoacids. It contains 51 amino acid arranged in two chains (A and B) joined together by disulfide linkage. In 1921, Banting and Best extracted insulin from the pancrease and demonstrated its therapeutic effects in diabetic dogs and human subjects.
Indication of Bovine Insulin
Bovine Insulin is primarily indicated in conditions like Diabetes mellitus, Hyperkalaemia.
Contraindication of Bovine Insulin
Bovine Insulin is contraindicated in conditions like Hypersensitivity.
Side Effects of Bovine Insulin
Bovine Insulin produces potentially life-threatening effects which include Hypoglycemia. which are responsible for the discontinuation of Bovine Insulin therapy.,The symptomatic adverse reactions produced by Bovine Insulin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Allergy, Lipoatrophy, Antibody formation.
Precautions of Bovine Insulin
It should be used with caution in case of bovine hypersensitivity, breast feeding, coma, diarrhea, fever, infections, porcine hypersensitivity, renal inpairment, surgery, thyroid disease, trauma, and vomiting.