Ursodeoxycholic Acid (Ursodeoxycholic Acid)
Overview of Ursodeoxycholic Acid
Ursodeoxycholic Acid is a secondary bile acid formed in the intestine. Ursodeoxycholic Acid is the 7-ß-hydroxy epimer of chenodiol (chenodeoxycholic acid). Chemically Ursodeoxycholic Acid is identified as 3a, 7 ß-dihydroxy-5 ß-cholan-24-oic acid. Ursodeoxycholic Acid is choleretic and decreases the concentration of cholesterol in bile. Ursodeoxycholic Acid is used to dissolve cholesterol gallstones, also effective for the treatment of primary biliary cirrhosis.
Indication of Ursodeoxycholic Acid
Ursodeoxycholic Acid is primarily indicated in conditions like Cholestrol gall stones, Dissolution of gallstones, Iron-deficiency anaemia with chronic renal failure.
Contraindication of Ursodeoxycholic Acid
Ursodeoxycholic Acid is contraindicated in conditions like Calcified gallstones,Non-functioning gallbladders,Pigment gallstone.
Side Effects of Ursodeoxycholic Acid
The symptomatic adverse reactions produced by Ursodeoxycholic Acid are more or less tolerable and if they become severe, they can be treated symptomatically, these include Diarrhea.
Precautions of Ursodeoxycholic Acid
Ursodeoxycholic acid should not be administered to patients with chronic liver disease, peptic ulcer or inflammatory bowel disease. Its use should be avoided in pregnancy.