Tretinoin (Tretinoin)
Overview of Tretinoin
Tretinoin is a vitamin A derivative. When applied topically, effective for the treatment of acne and to reudce photo-damage due to excessive exposure to sun light. Tretinoin is also used in conjuction with chemotherapy in the treatment of certain leukemias.
Indication of Tretinoin
Tretinoin is primarily indicated in conditions like Acne vulgaris, Promyelocytic leukemia, and can also be given in adjunctive therapy as an alternative drug of choice in Naevus comedonicus, Pseudofolliculitis, Senile comedones, Trichostasis spinulosa.
Contraindication of Tretinoin
No data regarding the contra indications of Tretinoin is available.
Side Effects of Tretinoin
The symptomatic adverse reactions produced by Tretinoin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Erythema, Irritation, Warmth feeling.
Precautions of Tretinoin
Tretinoin should be used with caution in patients with any illness or allergy, especially to any drug including parabens preservatives. It is recommended that persons using this medication not donate blood for at least three years after stopping therapy. It should not be used during pregnancy or lactation. Photosensitization may occur, caution patients to take protective measures, i.e.wearing protective clotting or sunscreen, before exposure to UV or sunlight. Use other acne preparation (if it is use topically) with caution while using tretinoin.