Timolol Maleate (Timolol Maleate)
Overview of Timolol Maleate
Timolol (Maleate) is a non-selective ß-blocking agent and blocks both ß1 and ß 2 adrenergic receptors. Timolol (Maleate) is similar in action but more potent than propranolol. Timolol (Maleate) is available for both systemic and ophthalmic use. It slows the heart rate and reduce hypertension and prevents the recurrence of myocardial infarction (MI) , but mainly used in glaucoma, by a local conjunctival instillation as eye drops.
Indication of Timolol Maleate
Timolol Maleate is primarily indicated in conditions like Angina, Glucoma, Hypertension, Iron deficiency anaemia, Migraine, Migraine prophylaxis, Myocardial infarction.
Contraindication of Timolol Maleate
Timolol (Maleate) is contraindicated in conditions like Cardiogenic shock,Heart block,Cardiac insufficiency,Obstructive airway disease.
Side Effects of Timolol Maleate
The severe or irreversible adverse effects of Timolol (Maleate), which give rise to further complications include Heart failure.,Timolol (Maleate) produces potentially life-threatening effects which include Asthma. which are responsible for the discontinuation of Timolol (Maleate) therapy.,The signs and symptoms that are produced after the acute overdosage of Timolol (Maleate) include Bradycardia, Bronchospasm.,The symptomatic adverse reactions produced by Timolol (Maleate) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Fatigue, Cold extremities, Insomnia, Bradycardia, Depression, Nausea and vomiting, Headedness, Paresthesias.
Precautions of Timolol Maleate
Timolol should be used with caution in diabetic patients or patients with liver or kidney impairments.