Sulpiride (Sulpiride)
Overview of Sulpiride
Sulpiride is antipsychotic agent with similar action and uses as for chlopromazine. Sulpiride is used in the treatment of schizophrenia, also given for the management of anxiety, vertigo and peptic ulceration.
Indication of Sulpiride
Sulpiride is primarily indicated in conditions like Control of muscarinic side-effects of neostigmine, Depression, Psychosis, Schizophrenia.
Contraindication of Sulpiride
Sulpiride is contraindicated in conditions like Epilepsy,Phaeochromocytoma,Porphyria.
Side Effects of Sulpiride
The severe or irreversible adverse effects of Sulpiride, which give rise to further complications include Tardive dyskinesia.,Sulpiride produces potentially life-threatening effects which include Hepatitis, Malignant neuroplastic syndrome, Hypertensive crises. which are responsible for the discontinuation of Sulpiride therapy.,The signs and symptoms that are produced after the acute overdosage of Sulpiride include Hypotension, Confusion, Agitation, Restlessness, Extrapyramidal effects.,The symptomatic adverse reactions produced by Sulpiride are more or less tolerable and if they become severe, they can be treated symptomatically, these include Irritability, Excitement, Anxiety, Parkinsonism, Akathisia, Acute dystonia, Elevated alkaline phosphatase, Mood swings, Leukopenia, Elevated aminotransferase.
Precautions of Sulpiride
Sulpiride should be given with care to manic or hypomanic patients in whom it may exacerbate symptoms. It should be used with care during pregnancy, avoid use during lactation. It should be used with caution in patients with impaired renal function.