Sulphacetamide (Sulphacetamide)
Overview of Sulphacetamide
Sulphacetamide is a synthetic sulfonamide antibiotic for ophthalmic or topical administration. Sulfacetamide, because Sulphacetamide is water soluble and because a 30% solution has a pH of 7.4, is an ideal sulfonamide for ophthalmic administration. Despite the favorable pharmaceutical properties, use of sulfonamides in general has declined due to development of resistance.
Indication of Sulphacetamide
Sulphacetamide is primarily indicated in conditions like Blepharitis, Conjuctivitis, Eye infections, Vaginosis.
Contraindication of Sulphacetamide
Sulphacetamide is contraindicated in conditions like Herpes simplex infections,Renal failure,Corneal infection.
Side Effects of Sulphacetamide
The severe or irreversible adverse effects of Sulphacetamide, which give rise to further complications include Conjunctivitis, Skin rashes, Corneal plaques.,Sulphacetamide produces potentially life-threatening effects which include Stevens Johnson syndrome, Erythema multiforme. which are responsible for the discontinuation of Sulphacetamide therapy.,The symptomatic adverse reactions produced by Sulphacetamide are more or less tolerable and if they become severe, they can be treated symptomatically, these include Blurred vision, Burning, Vaginal irritation, Stinging on application.
Precautions of Sulphacetamide
Consult with doctor about use of sulphacetamide during pregnancy or lactation.