Sucralfate (Sucralfate)
Overview of Sucralfate
Sucralfate is aluminium-sucrose complex, is a sulphated disaccharide developed for the treatment of peptic ulcer. It protects layer on gastro-duodenal mucosa by forming a complex with pepsin which adhere to active ulcers.
Indication of Sucralfate
Sucralfate is primarily indicated in conditions like Benign gastric and duodenal ulceration and chronic gastritis, Duodenal ulcer, Peptic ulcer, Prophylaxis of stress ulceration, Reflux oesophagitis, and can also be given in adjunctive therapy as an alternative drug of choice in Benign gastric and duodenal ulceration, Inflammatory bowel disease.
Contraindication of Sucralfate
No data regarding the contra indications of Sucralfate is available.
Side Effects of Sucralfate
The symptomatic adverse reactions produced by Sucralfate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Constipation.
Precautions of Sucralfate
Do not take antacids 30min before and after sucralfate. Avoid use in patients with renal impairment. It should be used in pregnancy if clearly needed.