Sodium Stibogluconate (Sodium Stibogluconate)
Overview of Sodium Stibogluconate
Sodium Stibogluconate is antiprotozoal, used in the treatment of all types of leishmaniasis along with other drugs (eg; pentamidine and amphotericin B).
Indication of Sodium Stibogluconate
Sodium Stibogluconate is primarily indicated in conditions like Leishmaniasis, Visceral leishmaniasis.
Contraindication of Sodium Stibogluconate
Sodium Stibogluconate is contraindicated in conditions like Renal diseases,Pneumonia,Liver diseases,Heart disease,Complicating secondary infection,Previous antimonial therapy.
Side Effects of Sodium Stibogluconate
The severe or irreversible adverse effects of Sodium Stibogluconate, which give rise to further complications include Venous thrombosis.,Sodium Stibogluconate produces potentially life-threatening effects which include Hepatotoxicity, Cardiotoxicity, Renal toxicity. which are responsible for the discontinuation of Sodium Stibogluconate therapy.,The signs and symptoms that are produced after the acute overdosage of Sodium Stibogluconate include Renal failure, Circulatory collapse, Disseminated intravascular coagulopathy.,The symptomatic adverse reactions produced by Sodium Stibogluconate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Anorexia, Myalgia, Malaise, Arthralgia, Nausea and vomiting.
Precautions of Sodium Stibogluconate
Safety of the sodium stibogluconate has not been determined in pregnant women , in the children <18 months and the breast feeding mothers.