Pyridoxine (Pyridoxine)
Overview of Pyridoxine
Pyridoxine, or vitamin B6, is a naturally occurring, water-soluble vitamin found in food such as cereal grains, legumes, vegetables, liver, meat, and eggs. Pyridoxine is used to treat and prevent vitamin B6 deficiency; to prevent or treat toxicity from isoniazid, cycloserine, or hydralazine; and to treat sideroblastic anemia associated with elevated serum iron levels. It also has been used in pyridoxine-dependent neonates to treat seizures that are unresponsive to conventional therapy and in patients with metabolic disorders such as xanthurenic aciduria, primary hyperoxaluria, primary cystathioninuria, and primary homocystinuria. Pyridoxine hydrochloride has been commercially available since approval by the FDA in 1940.
Indication of Pyridoxine
Indications
Contraindication of Pyridoxine
No data regarding the contra indications of Pyridoxine is available.
Side Effects of Pyridoxine
The severe or irreversible adverse effects of Pyridoxine, which give rise to further complications include Numbness, Neurotoxicity, Muscular weakness, Paresthesia, Hyperesthesia, Bone pain.,The signs and symptoms that are produced after the acute overdosage of Pyridoxine include Neuropathy, Hypervitaminosis.,The symptomatic adverse reactions produced by Pyridoxine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Drowsiness, Blurred vision, Pain, Burning.
Precautions of Pyridoxine
Some drugs increase pyridoxine requirements, these are cycloserine, hydralazine, isoniazid, oral contraceptives and penicillamine. It should be used with caution during lactation. Avoid long term administration of large doses of pyridoxine because may cause severe peripheral neuropathies.