Propantheline Br (Propantheline Br)
Overview of Propantheline Br
Propantheline (Br) is antimuscarinic with action, uses and adverse effects similar to those of atropine. Propantheline (Br) is used as an antispasmodic for gastro-intestinal and urinary complaints. Propantheline (Br) is also reduces the secretion of gastric acid and used in peptic ulcer disease.
Indication of Propantheline Br
Propantheline Br is primarily indicated in conditions like Adjunctive treatment of partial seizures, Diverticulitis, Duodenal ulcer, GI motality disorder, Hyperhidrosis, Menieres disease, Peptic ulcer, Symptomatic relief of GI-disorders, Urgency and incontinence, and can also be given in adjunctive therapy as an alternative drug of choice in Enuresis, Pancreatitis, Short bowel syndrome.
Contraindication of Propantheline Br
Propantheline (Br) is contraindicated in conditions like Cardiac arrhythmia,Glucoma,Reflux oesophagitis,Prostatic hypertrophy.
Side Effects of Propantheline Br
The severe or irreversible adverse effects of Propantheline (Br), which give rise to further complications include Tachycardia, Glaucoma, Orthostatic hypotension, Urinary retention.,Propantheline (Br) produces potentially life-threatening effects which include GI reactions, Cardiac arrhythmias. which are responsible for the discontinuation of Propantheline (Br) therapy.,The signs and symptoms that are produced after the acute overdosage of Propantheline (Br) include Respiratory arrest, Neuromuscular blockade.,The symptomatic adverse reactions produced by Propantheline (Br) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Impotence.
Precautions of Propantheline Br
Closely monitor patients for therapeutic response and side effects of propantheline. It should not used in high dose because may produce mental depression and mental distrubances. It should be used with caution in patients over 40yr because may increase the risk of glaucoma. It should be used with caution in patients with asthma, heart or renal (kidney) diseases. It should be used with caution in infants and small children.