Prilocaine (Prilocaine)
Overview of Prilocaine
Prilocaine is a local anesthetic of amide type with actions simlar to lidocaine. Prilocaine is used for anesthesia in minor surgical procedures such as dentistry.
Indication of Prilocaine
Prilocaine is primarily indicated in conditions like Infiltration anaesthesia (higher strengths for dental use only), Local anaesthesia, Local anaesthetic, Surgical anaesthesia, and can also be given in adjunctive therapy as an alternative drug of choice in Pain in short surgical procedure..
Contraindication of Prilocaine
Prilocaine is contraindicated in conditions like Anaemia,Methaemoglobinaemia.
Side Effects of Prilocaine
The severe or irreversible adverse effects of Prilocaine, which give rise to further complications include Skin rashes, Methemoglobinemia, Tremors, Porphyria, Hypersensitivity.,Prilocaine produces potentially life-threatening effects which include Tinnitus, Anxiety, Circumoral numbness, Cardiovascular depression, Cardiac Arrest. which are responsible for the discontinuation of Prilocaine therapy.,The signs and symptoms that are produced after the acute overdosage of Prilocaine include Seizures, CNS toxicity, Methemoglobinemia, Anxiety, Cyanosis, Numbness.,The symptomatic adverse reactions produced by Prilocaine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Vertigo, Nausea, Hypersensitivity reactions, Nystagmus.
Precautions of Prilocaine
Avoid Prilocain in patient with known hypersensitivity. It should be given with caution to the elderly, to debilitated, to children, patients with epilepsy, impaired cardiac conduction or respiratory function, shock or liver damage. It might be ototoxic and should not be instilled into the middle ear. The application of local anesthetics to the skin for prolonged period or to the extensive area should be avoided. It should be avoided in patients with anemia, congenital or acquired methaemoglobinaemia, cardiac or ventilatory failure or hypoxia. Be careful and avoid injury until anesthetic wears off.