Pirenzepine (Pirenzepine )
Overview of Pirenzepine
Pirenzepine (di HCl) is a selective M1 antimuscarinic agent, which has a preferential action on the gastric mucosa, causing reduced gastric acid secretion. Pirenzepine (di HCl) is used in the management of peptic ulcer disease.
Indication of Pirenzepine
Pirenzepine (di HCl) is primarily indicated in conditions like Benign gastric ulcer, Duodenal ulcer.
Contraindication of Pirenzepine
Pirenzepine (di HCl) is contraindicated in conditions like Renal failure.
Side Effects of Pirenzepine
The signs and symptoms that are produced after the acute overdosage of Pirenzepine (di HCl) include Anticholinergic effects.,The symptomatic adverse reactions produced by Pirenzepine (di HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dry mouth, Disturbances of accomodation.
Precautions of Pirenzepine
Pirenzepine should be used with caution in patients with renal (kidney) impairment, particularly those with end-stage renal failure. Avoid use in patients with angle closure glaucoma.