Ivermectin (Ivermectin)
Overview of Ivermectin
Ivermectin is anthelmintic agent. Ivermectin is a semisynthetic macrocyclic lactone. Ivermectin is a mixture of two closely related it compound B1a and B1b. Ivermectin is derived from the soil actinomycete Streptomyces avermitilis and effective against many nematodes and arthropod species.
Indication of Ivermectin
Ivermectin is primarily indicated in conditions like Lymphatic filariasis, Onchoceriasis, Strongyloides stercoralis, Strongyloidiasis.
Contraindication of Ivermectin
Ivermectin is contraindicated in conditions like Meningitis,Trypanosomiasis,Seizures,Hypersensitivity.
Side Effects of Ivermectin
The signs and symptoms that are produced after the acute overdosage of Ivermectin include Emesis, Mydriasis, Sedation.,The symptomatic adverse reactions produced by Ivermectin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Nausea, Diarrhea, Fever, Myalgia, Rashes, Pruritus, Cough, Arthralgia, Edema, Orthostatic hypotension, Sore throat, Lymphadenopathy, Lymph-node tenderness, dizziness.
Precautions of Ivermectin
Ivermectin should not be used in the pregnant or the breast feeding women or children < 5 years old or under 15 kg body weight. Patients with a history of the serious illness (i.e., hepatic , cardiovascular, renal or pulmonary disease, anemia, coagulation disorder, severe asthma etc) should receive the ivermecitin under extreme caution.