Isoetharine (Isoetharine)
Overview of Isoetharine
Isoetharine is a bronchodialator.It works by relaxing muscles in airways to improve breathing.,Isoetharine Hcl is a ß-2 selective catecholamine. Chemically Isoetharine Hcl is (R,S)-4-[1-hydroxy-2-[methylethyl) amino] butyl]-1, 2-benzenediol. Isoetharine Hcl is used as bronchodialator. It acts on the lung and dilate breathing passages making breathing easier. Isoetharine Hcl is used to prevent and treat bronchospasm in persons with certain lung diseases. Isoetharine Hcl is prepared by chemical synthesis and the racemate is used clinically.,Isoetharine (Mesylate) is a beta-adrenergic agonist, the actions and uses similar to those of isoprenaline but with less beta-1 stimulant properties. Isoetharine (Mesylate) is used as a bronchodilator in reversible airways obstructive disease. Isoetharine (Mesylate) is given orally or via inhalation.
Indication of Isoetharine
Isoetharine is primarily indicated in conditions like Acute bronchospasm, Asthma, Asthmatic bronchitis, Bronchitis, Chronic obstructive pulmonary disease, Emphysema.
Contraindication of Isoetharine
Isoetharine is contraindicated in conditions like Cardiac arrhythmia,Hypertension,Myocardial infarction,Thyrotoxicosis,Ischaemic heart disease,Subvalvular aortic stenosis,Hypersensitivity.
Side Effects of Isoetharine
The severe or irreversible adverse effects of Isoetharine, which give rise to further complications include Tachycardia, Palpitation, Headache, Extrasystoles, Intolerable muscle tremors, Breathing difficulty.,Isoetharine produces potentially life-threatening effects which include Cardiac Arrest, Ventilatory arrest. which are responsible for the discontinuation of Isoetharine therapy.,The signs and symptoms that are produced after the acute overdosage of Isoetharine include Nausea, Tachycardia, Dry mouth, Headache, Tremor, Restlessness, Anxiety, B.P. alteration, Excitement.,The symptomatic adverse reactions produced by Isoetharine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Weakness, Dizziness, Nausea, Vomiting, Palpitation, Insomnia, Irregular heart beat, Chest pain, Increase in heart rate.
Precautions of Isoetharine
Avoid intraneural or intravascular injection of isoetharine. Avoid situations that may trigger asthmatic attacks such as smoking,dry air etc The drug should be used with caution in the patient with cardiac diseases, AV block associated with digoxin toxicity, narrow-angle glaucoma, shock, during general anesthesia with halogenated agents or cyclopropane, diabetes and in psychoneurotic individuals.