Hydroxocobalamin (Hydroxocobalamin)
Overview of Hydroxocobalamin
Hydroxocobalamin is a cobalamine derivative in which the substituent is a hydroxyl group. Hydroxocobalamin is the natural form of the vitamin B12 and is sometime used as a source of vitamin B12.
Indication of Hydroxocobalamin
Hydroxocobalamin is primarily indicated in conditions like Anaemia, Congenital if deficiency, Congenital intrinsic factor deficiency, Ileal resection, Methylmalonylacidurias, Nutrition deficiency, Pernicious anaemia, Pernicious anaemia and other macrocytic anaemias, Prophylaxis of macrocytic anaemias, Thyrotoxicosis, Tobacco amblyopia, Tobacco amblyopia and leber's optic atrophy, Transcobalamin II deficiency, Vitamin deficiency, and can also be given in adjunctive therapy as an alternative drug of choice in Cyanide poisoning, Homocystenemia, Infected burns.
Contraindication of Hydroxocobalamin
Contraindications
Side Effects of Hydroxocobalamin
The severe or irreversible adverse effects of Hydroxocobalamin, which give rise to further complications include Hypersensitivity reactions.,Hydroxocobalamin produces potentially life-threatening effects which include Cardiac arrhythmia, Allergic reactions, Anaphylactic reactions, Hypocalcemia. which are responsible for the discontinuation of Hydroxocobalamin therapy.,The symptomatic adverse reactions produced by Hydroxocobalamin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Diarrhea, Nausea and vomiting, Hypokalemia, Red urine, Pain at injection site, Pain at injection site.
Precautions of Hydroxocobalamin
This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. Based on information of related products, this medication may pass into breast milk. Therefore, consult your doctor before breast-feeding.Avoid using in prematue infants