Hydroflumethiazide (Hydroflumethiazide)
Overview of Hydroflumethiazide
Hydroflumethiazide is a diuretic. It increases urination. Hydroflumethiazide is used in hypertention to lower the high blood pressure and also to treat fluid overload.
Indication of Hydroflumethiazide
Hydroflumethiazide is primarily indicated in conditions like Disorders of calcium balance, Edema, Heart failure, Hypertension, Oedema, and can also be given in adjunctive therapy as an alternative drug of choice in Diabetes insipidus.
Contraindication of Hydroflumethiazide
Hydroflumethiazide is contraindicated in conditions like Diabetes mellitus,Hypokalaemia.
Side Effects of Hydroflumethiazide
The severe or irreversible adverse effects of Hydroflumethiazide, which give rise to further complications include Thrombocytopenia, Pancreatitis, Cholestatic jaundice, Photosensitivity, Acute interstitial pulmonary edema, Skin rashes, Atherosclerosis, Necrotising vasculitis.,Hydroflumethiazide produces potentially life-threatening effects which include Hyponatremia, Hypokalemia, Cardiac arrhythmias, Abnormal lipid profile, Hypoplastic Anemia. which are responsible for the discontinuation of Hydroflumethiazide therapy.,The signs and symptoms that are produced after the acute overdosage of Hydroflumethiazide include Hypotension, Volume depletion, Hypokalemia, Renal failure, Hyponatremia.,The symptomatic adverse reactions produced by Hydroflumethiazide are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Thirst, Headache, Nausea, Gout, Impotence, Polyuria, Night cramps.
Precautions of Hydroflumethiazide
Thiazide diuretics increase sensitivity to sunlight, so avoid prolonged sun exposure, use a sunscreen and wear protective clothing. This medication should be used during pregnancy or lactation only if clearly needed. It should be used with caution in patients with gout or diabetes or any allergies especially to sulfa medications. Avoid any drugs that increase heart rate or cause excitation like decongestants (present in cough or cold products) because it may counter-act the blood pressure medicine.