Felodipine (Felodipine)
Overview of Felodipine
Felodipine is a calcium channel blocker. It lowers the blood pressure by blocking calcium, relaxes the heart muscle and dilates the heart blood vessels. It has been known since the late 1800s that calcium influx was necessary for the contraction of muscle. The discovery of calcium channel in a cardiac muscle was followed by the finding of several diffent type of calcium channel in diffrent tissues. These discoveries provided the necessary mechanisms for the triggering of cardiac and smooth muscle contraction. The discovery of these channels also made possible the developemnet of clinically useful blocking drugs.
Indication of Felodipine
Felodipine is primarily indicated in conditions like Angina, Hypertension, Prophylaxis of angina.
Contraindication of Felodipine
No data regarding the contra indications of Felodipine is available.
Side Effects of Felodipine
The signs and symptoms that are produced after the acute overdosage of Felodipine include Bradycardia, Hypotension, Excessive peripheral vasodilation.,The symptomatic adverse reactions produced by Felodipine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Fatigue, Palpitation, Rashes, Pruritus, Flushing, Ankle swelling, dizziness.
Precautions of Felodipine
Felodipine should be used with caution in patients with pre-existing heart disease or liver disease.This drug should be used only if clearly needed during pregnancy or lactation. Limit alcohol while taking this medication because it can enhance dizziness. Avoid drinking grapefruit juice at the same time when take this medication.This medication may cause enlargement of the gums, this can be minimized by maintaining good oral hygiene with regular brushing, flossing and massaging of the gums.