Amlodipine Besylate (Amlodipine Besylate)
Overview of Amlodipine Besylate
Amlodipine (Besylate) is a calcium channel blocker. It lowers the blood pressure, relaxes heart muscles and dilates the heart blood vessels to prevent spasm. It has been known since the late 1800s that calcium influx was necessary for the contraction of muscle.it inhibits the calcium influx across the cell membrane.it was approved by FDA in july1992 for clinical use.its long duration of action allows once daily dosage.
Indication of Amlodipine Besylate
Amlodipine (Besylate) is primarily indicated in conditions like Angina pectoris, Essential hypertension, Hypertension, Prophylaxis of angina, Vasospastic angina.
Contraindication of Amlodipine Besylate
Amlodipine (Besylate) is contraindicated in conditions like Aortic stenosis,Sinoatrial node disease,Hypersensitivity.
Side Effects of Amlodipine Besylate
The severe or irreversible adverse effects of Amlodipine (Besylate), which give rise to further complications include Peripheral edema, Sinus bradycardia.,Amlodipine (Besylate) produces potentially life-threatening effects which include Myocardial infarction. which are responsible for the discontinuation of Amlodipine (Besylate) therapy.,The signs and symptoms that are produced after the acute overdosage of Amlodipine (Besylate) include Hypotension, Bradyarrhythmias, Congestive heart failure, Conduction system Delay.,The symptomatic adverse reactions produced by Amlodipine (Besylate) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Flatulence, Dizziness, Vertigo, Headache, Drowsiness, Fatigue, Nausea, Vomiting, Diarrhea, Palpitation, Tremors, Constipation, Abdominal pain, Blurred vision, Peripheral edema, Skin erythema, Facial flushing, Hypotension, Coughing, Flushing, Syncope, Wheezing, dysthesia.
Precautions of Amlodipine Besylate
Amlodipine should be used with caution in patients with heart, liver disease or if have any allergy. Limit intake of alcohol while taking this drug. This medication should be used with extreme caution during pregnancy.