Desipramine Hcl (Desipramine Hcl)
Overview of Desipramine Hcl
Desipramine Hcl is a tricyclic antidepressant. Desipramine Hcl is the monodemethyl derivative of imipramine and Desipramine Hcl is less sedating than its parent compound. Two to three weeks are required to obtain the full effects of the drug. It may also be used to treat nerve pain, insomnia and bed-wetting in children.
Indication of Desipramine Hcl
Desipramine Hcl is primarily indicated in conditions like Cocaine addiction, Depression prophylaxis, Depression treatment, Enuresis.
Contraindication of Desipramine Hcl
Desipramine (HCl) is contraindicated in conditions like Cardiac arrhythmia,Mania,Myocardial infarction,Heart block,Hepatic disease,Narrow-angle glaucoma,Urinary retention.
Side Effects of Desipramine Hcl
The severe or irreversible adverse effects of Desipramine (HCl), which give rise to further complications include Hepatitis, Agranulocytosis.,The signs and symptoms that are produced after the acute overdosage of Desipramine (HCl) include Hypotension, Coma, Epileptic seizures, Respiratory depression, Respiratory depression, Tremor, Ventricular arrhythmias, Delayed cardiac conduction, Respiratory depression.,The symptomatic adverse reactions produced by Desipramine (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Drowsiness, Nausea, Anxiety, Palpitation, Abdominal pain, Sleep disturbancesX, Dry mouth, Blurred vision, Confusion, Pruritus, Sedation, Photosensitivity, Weight gain, Tremor, Postural hypotension, Mydriasis, Allergic skin reactions, Vasculitis, Xerostomia, Erectile impotence, Urinary RetentionX, Urinary retention, Dry mouth, Confusion, dizziness.
Precautions of Desipramine Hcl
Desipramine should be used with caution (if it contains tartrazine) in patients with aspirin hypersensitivity, because it may produce allergic reaction (including bronchial asthma). Monitor ECG before initiating large doses of tetracyclines. Avoid concurrent administration with electric shock therapy because may increase the hazards of therapy. Perform periodic leukocytes (white blood cells) counts and liver function tests. Photosensitization may occur so caution patients to take protective measures, sunscreens etc, against exposure to UV light or sun light.