cyclobenzaprine hydrochloride (cyclobenzaprine hydrochloride)
Overview of cyclobenzaprine hydrochloride
Cyclobenzaprine hydrochloride is a tricyclic amine salt with the empirical formula C20H21N�HCl. Cyclobenzaprine is a central nervous system (CNS) muscle relaxant intended for short-term use in the treatment of pain, tenderness, and limitation of motion caused by muscle spasms. It is thought to act within the CNS at the brain stem rather than spinal cord levels, although action at the spinal cord level may contribute to some of its skeletal muscle relaxant action.
Indication of cyclobenzaprine hydrochloride
cyclobenzaprine hydrochloride is primarily indicated in conditions like Muscle relaxation, Muscular spasm, Pain.
Contraindication of cyclobenzaprine hydrochloride
cyclobenzaprine hydrochloride is contraindicated in conditions like Hyperthyroidism,Congestive heart failure,Hypersensitivity to any component of product.
Side Effects of cyclobenzaprine hydrochloride
The severe or irreversible adverse effects of cyclobenzaprine hydrochloride, which give rise to further complications include Irregular heart beat.,cyclobenzaprine hydrochloride produces potentially life-threatening effects which include Hypersensitivity reactions. which are responsible for the discontinuation of cyclobenzaprine hydrochloride therapy.,The signs and symptoms that are produced after the acute overdosage of cyclobenzaprine hydrochloride include Nausea, Vomiting, Tachycardia, Coma, Seizures, Cardiac dysrhythmias, Drowsiness, Changes in ECG, Confusion, Hallucinations, Ataxia, Severe hypotension, Dizziness, Tremor, Agitation, Hypertension, Slurred speech.,The symptomatic adverse reactions produced by cyclobenzaprine hydrochloride are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Drowsiness, Fatigue, Nausea, Diarrhea, Constipation, Abdominal pain, Dry mouth, Acid regurgitation.
Precautions of cyclobenzaprine hydrochloride
Use of Cyclobenzaprine Hydrochloride for periods longer than two or three weeks is not recommended. Less frequent dosing should be considered for hepatically impaired or elderly patients. It is contraindicated in acute recovery phase of myocardial infarction, and patients with arrhythmias, heart block or conduction disturbances, or congestive heart failure. it should be used with caution in elderly patients with reduced doses. It should be used with caution in patients with a history of urinary retention, angleclosure glaucoma, increased intraocular pressure, and in patients taking anticholinergic medication. It should be used with caution in subjects with mild hepatic impairment starting with a 5 mg dose and titrating slowly upward. In subjects with moderate to severe impairment is not recommended. Safety and effectiveness of cyclobenzaprine hydrochloride in pediatric patients below 15 years of age have not been established.