Sargramostim (Sargramostim)
Overview of Sargramostim
Sargramostim is a highly purified glycosylated protein consisting of 127 a.a,produced by recombinant DNA synthesis in yeast culture.It stimulates production of WBC.
Indication of Sargramostim
Sargramostim is primarily indicated in conditions like Acute myeloid leukemia, Bone marrow transplantation, and can also be given in adjunctive therapy as an alternative drug of choice in Infections, Neutropenia.
Contraindication of Sargramostim
Sargramostim is contraindicated in conditions like Myeloblastic leukemia,Hypersensitivity.
Side Effects of Sargramostim
The severe or irreversible adverse effects of Sargramostim, which give rise to further complications include Allergic reactions, Weight gain, Dizziness, Chest pain.,The signs and symptoms that are produced after the acute overdosage of Sargramostim include Nausea, Shortness of breadth, Fever, Rashes.,The symptomatic adverse reactions produced by Sargramostim are more or less tolerable and if they become severe, they can be treated symptomatically, these include Diarrhea, Bone pain, Muscle aching, Loss of appetite.
Precautions of Sargramostim
Sargramostim should be used in pregnancy if clearly needed. Cautions should be taken if patient is taking other chemotherapeutic drugs.