Semustine (Semustine)
Overview of Semustine
Semustine is a nitrosourea. It is one of group of antineoplastic drugs known as alkylating agent.
Indication of Semustine
Semustine is primarily indicated in conditions like Brain tumors, Colorectal cancer, Lymphomas, Stomach cancer.
Contraindication of Semustine
Semustine is contraindicated in conditions like Hypersensitivity.
Side Effects of Semustine
The severe or irreversible adverse effects of Semustine, which give rise to further complications include Renal damage, Thrombocytopenia.,The signs and symptoms that are produced after the acute overdosage of Semustine include Convulsions, Pulmonary fibrosis, Leucopenia, Optic neuritis.,The symptomatic adverse reactions produced by Semustine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea and vomiting, Hyperpigmentation.
Precautions of Semustine
Used with caution in children who are at risk of severe delayed pul;monary toxicity, reduced lung function. Blood counts should be monitored weekly. Renal and hepatic functions should be monitored periodically.