Nimorazole (Nimorazole)
Overview of Nimorazole
Nimorazole is a 5-nitroimidazole derivative. It has antimicrobial actions and uses similar to those of metronidazole.
Indication of Nimorazole
Nimorazole is primarily indicated in conditions like Amoebiasis, Giardiasis, Trichomoniasis, and can also be given in adjunctive therapy as an alternative drug of choice in Gingivitis.
Contraindication of Nimorazole
Nimorazole is contraindicated in conditions like Liver diseases,Hypersensitivity,Pregnancy,Kidney disease,Breast feeding.
Side Effects of Nimorazole
The signs and symptoms that are produced after the acute overdosage of Nimorazole include Convulsions, Seizures, Leucopenia, Peripheral neuropathy.,The symptomatic adverse reactions produced by Nimorazole are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Drowsiness, Ataxia, Diarrhea, Insomnia, Skin rashes, Pain, Allergic reactions, Itching, Nausea and vomiting, Heart burn.
Precautions of Nimorazole
During treatment is not recommended to drink alcoholic beverages. Peripheral neuropathy, transient epileptiform seizures, and leucopenia have sometimes been associated with prolonged or intensive treatment with Nimorazole. Clinical and laboratory monitoring is advised in patients receiving Nimorazole for more than 10 days. Doses should be reduced in patients with severe hepatic impairment. It is suggested that the use of Nimorazole should be avoided during pregnancy, and this caution applies especially to use during the first trimester and to the use of high-dose regimens.