Mitotane (Mitotane)
Overview of Mitotane
Mitotane is an antineoplastic similar to the insecticide DDT; used for the treatment of inoperable adrenocortical carcinoma.
Indication of Mitotane
Mitotane is primarily indicated in conditions like Cushing's syndrome.
Contraindication of Mitotane
Mitotane is contraindicated in conditions like Hypersensitivity.
Side Effects of Mitotane
Mitotane produces potentially life-threatening effects which include Anemia, Thrombocytopenia, Leucopenia, Anemia. which are responsible for the discontinuation of Mitotane therapy.,The signs and symptoms that are produced after the acute overdosage of Mitotane include Blurred vision, Polyneuropathy, Hyperpyrexia, Hypertension, Mycoses, Polyneuropathy, Retinopathy.,The symptomatic adverse reactions produced by Mitotane are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Vertigo, Headache, Fatigue, Ataxia, Nausea, Vomiting, Anorexia, Diarrhea, Confusion, Lethargy, Sedation, Depression, Diplopia, Gynecomastia, Epigastric pain, Anemia, Increased bleeding time, Confusion, Sore mouth, dizziness, Ataxia.
Precautions of Mitotane
Avoid MITOTANE in severe liver disease Monitor serum concentration of MITOTANE in liver disease Manufacturer advises caution with MITOTANE in liver disease