Colistin (Sulphate & Sulphomethate Na) (Colistin (Sulphate & Sulphomethate Na))
Overview of Colistin (Sulphate & Sulphomethate Na)
Colistin (Sulphate and Sulphomethate Na) is antibiotic and is used to treat bacterial infections. Colistin is marketed only for oral administration in the treatment of intestinal infections. Colistin (Sulphate and Sulphomethate Na) is also used topically in the treatment of some external ear infections. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the drug at regular interval of time throughout the day and night as prescribed. Colistin (Sulphate and Sulphomethate Na) is important to take the drug for the full time period as prescribed. If you discontinue the drug it may result in ineffective treatment.
Indication of Colistin (Sulphate & Sulphomethate Na)
Colistin (Sulphate & Sulphomethate Na) is primarily indicated in conditions like Benign gastric and duodenal ulcers, Bladder irrigation, Bowel sterilization, Decontamination of digestive tract, GI infections, Metastatic germ cell cancer, Oedema, Oliguria due to renal failure, Respiratory tract infections, Superficial infections, Systemic infections, and can also be given in adjunctive therapy as an alternative drug of choice in Cystic fibrosis.
Contraindication of Colistin (Sulphate & Sulphomethate Na)
Colistin (Sulphate & Sulphomethate Na) is contraindicated in conditions like Myasthenia gravis,Pregnancy,Breast feeding.
Side Effects of Colistin (Sulphate & Sulphomethate Na)
The severe or irreversible adverse effects of Colistin (Sulphate & Sulphomethate Na), which give rise to further complications include kidney dysfunction.,Colistin (Sulphate & Sulphomethate Na) produces potentially life-threatening effects which include Nephrotoxicity, Neurotoxicity. which are responsible for the discontinuation of Colistin (Sulphate & Sulphomethate Na) therapy.,The signs and symptoms that are produced after the acute overdosage of Colistin (Sulphate & Sulphomethate Na) include Apnea, Renal insufficiency, Muscle weakness.,The symptomatic adverse reactions produced by Colistin (Sulphate & Sulphomethate Na) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Vertigo, Vomiting, Fever, Confusion, Urticaria, Peripheral neuropathy, Circumoral paresthesia, Respiratory insufficiency, Muscular weakness, Confusion, dizziness.
Precautions of Colistin (Sulphate & Sulphomethate Na)
Renal impairment; porphyria; risk of bronchospasmon inhalation---may be prevented or treated with a selective beta2 agonist. Colistin should be used with caution in patients who are sensitive to aminoglycosides.Take appropriate measures in case of secondry infections.