Colestipol Hcl (Colestipol Hcl)
Overview of Colestipol Hcl
Colestipol Hcl is antihyperlipidimic agent. Chemically Colestipol Hcl is a copolymer of diethylenetriamine and 1-chloro-2, 3-epoxypropane. Colestipol Hcl is very large polymeric anion-exchange resins that is insoluble in water. Colestipol Hcl is effective in reducing the high levels of cholesterol in blood.
Indication of Colestipol Hcl
Colestipol Hcl is primarily indicated in conditions like Atherosclerosis, Bile salt-induced diarrhoea, Digitalis toxicity, Digitoxin toxication, Familial hypercholesterolaemia, Hypercholesterolaemia, Partial biliary obstruction-induced pruritus, Prophylaxis of NSAID-associated gastric or duodenal ulcer, Prophylaxis of NSAID-associated gastric or duodenal ulcer.
Contraindication of Colestipol Hcl
Colestipol (HCl) is contraindicated in conditions like Intestinal obstruction,Diverticulitis,Anal fissure,Hernia.
Side Effects of Colestipol Hcl
The severe or irreversible adverse effects of Colestipol (HCl), which give rise to further complications include Constipation.,The signs and symptoms that are produced after the acute overdosage of Colestipol (HCl) include Intestinal obstruction.,The symptomatic adverse reactions produced by Colestipol (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Flatulence, Nausea, Vomiting, Diarrhea, Constipation, Heart burn, Abdominal discomfort.
Precautions of Colestipol Hcl
Before starting therapy, investigate and treat diseases like diabetes mellitus, hypothyroidism, dysproteinemias or liver diseases. With long term therapy, supplemental vitamin A and D may be given. Periodically measure serum triglyceride level to detect significant changes. These agents may produced or severely worsen pre-existing constipation. A laxatives, stool softener or increased fluid intake may be helpful.