Propiverine Hydrochloride (Propiverine Hydrochloride)
Overview of Propiverine Hydrochloride
Smooth muscle relaxant with actions combining the effects of anticholinergics & calcium channel blockers, used orally to relax the bladder muscles in incontinence from spinal cord leisons or unstable bladder conditions. It may cause dry mouth, blurred vision & drowsiness.
Indication of Propiverine Hydrochloride
Propiverine Hydrochloride is primarily indicated in conditions like Neurogenic bladder, Severe nausea and vomiting, Urgency and incontinence, and can also be given in adjunctive therapy as an alternative drug of choice in Urinary frequency,urgency and incontinence.
Contraindication of Propiverine Hydrochloride
Propiverine Hydrochloride is contraindicated in conditions like Glucoma,Myasthenia gravis,Gastro-intestinal atony,Phobic and obsessional states,For termination of pregnancy,Pregnancy,Urinary retention,Breast feeding.
Side Effects of Propiverine Hydrochloride
The symptomatic adverse reactions produced by Propiverine Hydrochloride are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Drowsiness, Nausea, Vomiting, Diarrhea, Palpitation, Tachycardia, Skin reactions, Constipation, Dry mouth, Blurred vision, Faintness, Angioedema, Abdominal discomfort, CNS stimulation, Difficulty in micturation.
Precautions of Propiverine Hydrochloride
Propiverine Hydrochloride should be used with caution in the elderly (especially if frail) and in those with autonomic neuropathy. It should also be used with caution in Hiatus hernia with reflux esophagitis, & in Hepatic impairment & Renal impairment. Antimuscarinics may worsen Hyperthyroidism, Coronary artery disease, Congestive heart failure, Prostatic hypertrophy, Arrhythmias & Tachycardia.