Duloxetine Hydrochloride (Duloxetine Hydrochloride)
Overview of Duloxetine Hydrochloride
Duloxetine hydrochloride is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI) for oral administration. Its chemical designation is (+)-(S)-N-methyl-?-(1-naphthyloxy)-2-thiophenepropylamine hydrochloride. The empirical formula is C18H19NOS�HCl. Duloxetine hydrochloride is a white to slightly brownish white solid, which is slightly soluble in water.
Indication of Duloxetine Hydrochloride
Duloxetine Hydrochloride is primarily indicated in conditions like Anxiety disorder, Depression, Urinary incontinence, and can also be given in adjunctive therapy as an alternative drug of choice in Moderate to severe stress urinary incontinence in women.
Contraindication of Duloxetine Hydrochloride
No data regarding the contra indications of Duloxetine Hydrochloride is available.
Side Effects of Duloxetine Hydrochloride
The severe or irreversible adverse effects of Duloxetine Hydrochloride, which give rise to further complications include Hyponatremia, Hyponatremia.,The symptomatic adverse reactions produced by Duloxetine Hydrochloride are more or less tolerable and if they become severe, they can be treated symptomatically, these include Weakness, Thirst, Fatigue, Nausea, Vomiting, Diarrhea, Constipation, Insomnia, Sweating, Blurred vision, Pruritus, Lethargy, Dyspepsia, Weight gain, Somnolence, Tremor, Sexual dysfunction, Syncope, Decrease in libido, dyspepsia.
Precautions of Duloxetine Hydrochloride
Elderly, History of mania, History of seizures; Raised ocular pressure, Acute narrow- angle glucoma; Concomitant use of drugs that increase risk of bleeding; Suicidal thoughts or behaviour; assess benefit of treatment periodically; avoid abrupt withdrawl. The drug should not be administered to lactating mothers, pregnant mothers and hepatic patients.