Rizatriptan (Rizatriptan)
Overview of Rizatriptan
Rizatriptan is a 5 -HT 1 agonist, used in the treatment of an acute migraine attack.
Indication of Rizatriptan
Rizatriptan is primarily indicated in conditions like Long-term treatment of reflux oesophagitis, Mild to moderate dementia in alzheimer's disease.
Contraindication of Rizatriptan
Rizatriptan is contraindicated in conditions like Peripheral vascular disease,Ischaemic heart disease,Cerebrovascular accident,Uncontrolled hypertension.
Side Effects of Rizatriptan
The symptomatic adverse reactions produced by Rizatriptan are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Vertigo, Thirst, Fatigue, Myalgia, Dyspnea, Palpitation, Tachycardia, Insomnia, Nervousness, Sweating, Blurred vision, Urticaria, Pruritus, Dyspepsia, Flushing, Tremor, Asthenia, Tingling, Sensation of warmth, Heaviness.
Precautions of Rizatriptan
5HT1 agonists (e.g Rizatriptan) should be used with caution in conditions which predispose to coronary artery disease (pre-existing cardiac disease), pregnancy and breast-feeding. 5HT1 agonists are recommended as monotherapy and should not be taken concurrently with other acute migraine therapies. Little information is available on the use of these drugs in the elderly (over 65 year). Caution is also required in mild or moderate hepatic impairment and renal impairment; not to be taken until 24 hours after stopping ergotamine-type prepration (ergotamine-type prepration not to be taken until 6 hours after Rizatriptan)