Trastuzumab (Trastuzumab)
Overview of Trastuzumab
An antineoplastic drug, it is given in combination with paclitaxel or docetaxel, for metastatic breast cancer and in whom anthracycline treatment is inappropriate. It may be given as a monotherapy. It is given by IV-infusion.
Indication of Trastuzumab
Trastuzumab is primarily indicated in conditions like Metastatic breast cancer, Metastatic carcinoma of breast.
Contraindication of Trastuzumab
Trastuzumab is contraindicated in conditions like Breast feeding,Severe dyspnea at rest.
Side Effects of Trastuzumab
The severe or irreversible adverse effects of Trastuzumab, which give rise to further complications include Congestive heart failure, Cardiovascular toxicity, Ventricular dysfunction, Thromboembolic stroke.,The symptomatic adverse reactions produced by Trastuzumab are more or less tolerable and if they become severe, they can be treated symptomatically, these include Inflammation, Dizziness, Headache, Anorexia, Diarrhea, Fever, Dyspnea, Insomnia, Chills, Rashes, Pain, Cough, Nausea and vomiting, Edema, Anemia, Leukopenia, Paresthesias, Infusion reactions, 1st dose, Infection.
Precautions of Trastuzumab
Symptomatic heart failure History of hypertension Coronary artery disease Pregnancy CARDIOTOXICITY:Monitor cardiac function of all patients before and during treatment. Herceptin therapy should be used with caution in patients with known hypersensitivity to Trastuzumab, chinese Hamster ovary cell proteins, or any component of this product.