Chlortetracycline Hcl (Chlortetracycline Hcl)
Overview of Chlortetracycline Hcl
Chlortetracycline is a broad spectrum tetracycline antibiotic. Tetracyclines are derivative of polycyclic naphthacenecarboxamide. They are bacteriostatic and effective against many gram positive and gram negative bacteria. Chlortetracycline is isolated from Streptomyces aureofaciens. It was introduced in 1948 and was the first of the tetracycline group to be discovered. Chlortetracycline Hcl is used as an antibacterial and antiprotozoal administered orally, by intravenous injection, or applied topically to the conjuctiva. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the drug at regular interval of time throughout the day and night as prescribed. Chlortetracycline Hcl is important to take the drug for the full time period as prescribed. If you discontinue the drug, it may result in ineffective treatment.
Indication of Chlortetracycline Hcl
Chlortetracycline Hcl is primarily indicated in conditions like Acne, Bacterial infections, Genitourinary tract infections, GI infections, Opthalmic infections, Pneumonia, Pyogenic infections, Respiratory tract infections, Soft tissue infections.
Contraindication of Chlortetracycline Hcl
Chlortetracycline (HCl) is contraindicated in conditions like Systemic lupus erythematosus,Renal impairment,Hepatic impairment,Hypersensitivity.
Side Effects of Chlortetracycline Hcl
The severe or irreversible adverse effects of Chlortetracycline (HCl), which give rise to further complications include Staining of developing teeth, Hypoplasia of enamel, Superinfection, Sever sun burn, Gastric discomfort.,Chlortetracycline (HCl) produces potentially life-threatening effects which include Phototoxicity, Fatal liver damage, Anaphylaxis, effects on classified tissues, Hepatic necrosis, fatal neciosis, Fatal liver damage. which are responsible for the discontinuation of Chlortetracycline (HCl) therapy.,The signs and symptoms that are produced after the acute overdosage of Chlortetracycline (HCl) include Hypotension, Nausea, Vomiting, Coma, Jaundice, Raised hepatic enzymes, Abdominal pain, Intestinal hemorrhage, Lethargy, Jaundice.,The symptomatic adverse reactions produced by Chlortetracycline (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Anorexia, Diarrhea, Skin rashes, Stomatitis, Vaginitis, Glossitis, Hemolytic anemia, Thrombocytopenia, Intracranial hypertension, Enterocolitis, Bulging fontanelle in Infants, Anogenital inflammatory lesions, Skin rashes, Vestibular problems.
Precautions of Chlortetracycline Hcl
Use chlortetracycline with caution (if contain tartrazine) in patients with aspirin hypersensitivity, because it may cause allergic reactions (including bronchial asthma). Take appropriate measures if secondary infection occurs. Perform periodic lab evaluation of organ system (e.g. liver or kidney) in case of long term therapy. It should be used with caution during pregnancy or lactation.