Capecitabine (Capecitabine)
Overview of Capecitabine
Capecitabine is an antimetaboite antineoplastic (anticancer) drug,which is metabolised to fluorouracil. Capecitabine is given by mouth and used as amonotherapy for metastatic colorectal carcinoma. Capecitabine is also licensed for second line treatment of locally advanced or metastatic breast cancer either in combination ao alone.
Indication of Capecitabine
Capecitabine is primarily indicated in conditions like Breast cancer, Metastatic, Metastatic colorectal cancer.
Contraindication of Capecitabine
No data regarding the contra indications of Capecitabine is available.
Side Effects of Capecitabine
The severe or irreversible adverse effects of Capecitabine, which give rise to further complications include Thrombocytopenia, Hyperbilirubinemia.,The symptomatic adverse reactions produced by Capecitabine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Fatigue, Nausea, Vomiting, Anorexia, Diarrhea, Fever, Constipation, Abdominal pain, Erythema, StomatitisX, Dermatitis, Eye irritation, Paresthesias, Desquamation of hands.
Precautions of Capecitabine
Avoid use in patient with a history of hypersensitivity to capecitabine, fluorouracil or any component. It is classified as pregnancy category D and should be used only when the benefit of therapy outweigh the risk to fetus.