Paromomycin sulphate (Paromomycin sulphate)
Overview of Paromomycin sulphate
Paromomycin (Sulphate) is an aminoglycoside antibiotic. The antibacterial spectrum is similar to that of neomycin, but is also effcetive against some protozoa, including Leishmania spp., Entamoeba histolytica, and crytosporidium spp.and anthelminitic properties against tape worms. Cross resistance may produce beween paromomycin and kanamycin, neomycin and streptomycin. Paromomycin (Sulphate) is used in the treatment of intestinal protozoal infections, including amoebiasis, cryptosporidiosis, visceral or cutaneous leishmmaniasis and giardiasis. It may also be used in the treatment of tapeworm infection.
Indication of Paromomycin sulphate
Paromomycin Sulphate is primarily indicated in conditions like Amoebiasis, Cryptosporidiosis, Giardiasis, Hepatic encephalopathy, Intestinal protozoal infection.
Contraindication of Paromomycin sulphate
Paromomycin (Sulphate) is contraindicated in conditions like Intestinal obstruction,Amebiasis,Hypersensitivity to the drug.
Side Effects of Paromomycin sulphate
The severe or irreversible adverse effects of Paromomycin (Sulphate), which give rise to further complications include Nephrotoxicity, Ototoxicity.,The symptomatic adverse reactions produced by Paromomycin (Sulphate) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Diarrhea, Nausea and vomiting.
Precautions of Paromomycin sulphate
It should be used with caution in patients who are sensitive to aminoglycosides. Take appropriate measures in case of secondry infections.