Cephradine (Cephradine)
Overview of Cephradine
Cephradine is a first generation, semisynthetic analogue of natural cephalosporin antibiotic. Cephalosporins are derivatives of 7-aminocephalosporic acid and are closely related to penicillins in structure. Cephalosporins have a six membered sulfur containing ring adjoining a ß lactam ring. Cephradine is effective against gram positive and gram negative bacterias. Administered orally or by intramuscularly or by intravenous injection. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the medication at regular interval of time throughout the day and night as prescribed. Cephradine is important to take the drug for the full time period as prescribed. If you discontinue the therapy, it may result in ineffective treatment.
Indication of Cephradine
Cephradine is primarily indicated in conditions like Bone and joint infection, Genitourinary tract infections, Lower respiratory tract infections, Pharyngitis, Pneumonia, Prostatitis, Respiratory tract infections, Skin infections, Soft tissue infections, Surgical prophylaxis, Tonsillitis, Upper respiratory tract infections, and can also be given in adjunctive therapy as an alternative drug of choice in Bacterial infections.
Contraindication of Cephradine
Cephradine is contraindicated in conditions like Hypersensitivity.
Side Effects of Cephradine
The severe or irreversible adverse effects of Cephradine, which give rise to further complications include Pseudomembranous colitis, Hypersensitivity reactions, Seizures, Superinfection.,Cephradine produces potentially life-threatening effects which include Thrombophelebitis, Anaphylactic reactions. which are responsible for the discontinuation of Cephradine therapy.,The signs and symptoms that are produced after the acute overdosage of Cephradine include Nausea, Convulsions, Severe diarrhea.,The symptomatic adverse reactions produced by Cephradine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Diarrhea, Skin rashes, Vaginitis, Local pain.
Precautions of Cephradine
Cephradine should be used with caution in patients with impaired kidney or liver function. Appropriate measure should be taken if secondary infection occurs.