Cephazolin Na (Cephazolin Na)
Overview of Cephazolin Na
Cephazolin is a first-generation cephalosporin antibiotic. Cephalosporins are derivatives of 7-aminocephalosporic acid and are closely related to penicillins in structure. Cephalosporins have a six membered sulfur containing ring adjoining a ß lactam ring. Cephazolin is effective in a large variety of bacterial infections, such as respiratory tract, skin and urinary tract infections. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the medication at regular interval of time throughout the day and night as prescribed. Cephazolin (Na) is important to take the drug for the full time period as prescribed. If you discontinue the therapy, it may result in ineffective treatment.
Indication of Cephazolin Na
Cephazolin Na is primarily indicated in conditions like Bacterial infections, Bone and joint infection, Endocarditis, Genitourinary tract infections, Peritonitis, Persistant neutropenia in advanced hiv infection, Respiratory tract infections, Septicaemia, Skin infections, Soft tissue infections, and can also be given in adjunctive therapy as an alternative drug of choice in Biliary tract disorders, Bronchiectasis, Bronchogenic carcinoma, Pneumonia.
Contraindication of Cephazolin Na
Cephazolin (Na) is contraindicated in conditions like Pregnancy,Hypersensitivity to any component of product.
Side Effects of Cephazolin Na
The severe or irreversible adverse effects of Cephazolin (Na), which give rise to further complications include Convulsions, Thrombocytopenia, Hypersensitivity reactions, Eosinophilia, Eosinophilia, Leucopenia, Neutropenia.,Cephazolin (Na) produces potentially life-threatening effects which include Pseudomembranous colitis, Anaphylactic reactions. which are responsible for the discontinuation of Cephazolin (Na) therapy.,The symptomatic adverse reactions produced by Cephazolin (Na) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Anorexia, Diarrhea, Genital and anal pruritus, Genital moniliasis, Transient rise in SGPT & SGOT, Rise in blood urea levels.
Precautions of Cephazolin Na
Cephazolin should be used with caution in patients with impaired kidney or liver function. Appropriate measure should be taken if secondary infection occurs. It should be used with caution (if contains tartrazine) in patients with aspirin hypersensitivity, because it may cause allergic reactions (including bronchial asthma).