Idarubicin Hcl (Idarubicin Hcl)
Overview of Idarubicin Hcl
Idarubicin Hcl is antineoplastic agent or anticancer drug. Idarubicin Hcl is a synthetic analog of anthracycline daunorubicin. Idarubicin differ from daunorubicin by the absence of methoxy group at the C-4 position. Idarubicin Hcl is effective in the treatment of different types of cancers. Idarubicin Hcl is used in combination of other anticancer drugs to obtain best therapeutic effects and to reduce toxicity or side effects. It has less potentially less cardiotoxicity than doxorubicin and daunorubicin.Idarubicin Hcl is administered orally or intravenously.
Indication of Idarubicin Hcl
Idarubicin Hcl is primarily indicated in conditions like Acute erythroleukemia, Acute myelogenous leukemia, Acute non-lymphoblastic leukemia, Acute non-lymphocytic leukaemia, Acute promyelocytic leukemia, Advanced breast cancer, Advanced breast or prostate cancer, and can also be given in adjunctive therapy as an alternative drug of choice in Breast cancer, Multiple myeloma, Non-hodgkin's lymphoma, Non-hodgkin's lymphoma.
Contraindication of Idarubicin Hcl
Idarubicin (HCl) is contraindicated in conditions like Bone marrow suppression.
Side Effects of Idarubicin Hcl
The severe or irreversible adverse effects of Idarubicin (HCl), which give rise to further complications include Urticaria, Neutropenia, Seizures, Cardiomyopathy, Pancytopenia, Leukopenia.,Idarubicin (HCl) produces potentially life-threatening effects which include Congestive heart failure, Myelosuppression, Fatal arrhythmias. which are responsible for the discontinuation of Idarubicin (HCl) therapy.,The signs and symptoms that are produced after the acute overdosage of Idarubicin (HCl) include Arrhythmias.,The symptomatic adverse reactions produced by Idarubicin (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Vomiting, Alopecia, Diarrhea, Mucositis, Abdominal pain, Cardiac arrhythmias, StomatitisX, Anemia, Discoloration of urine, Sinus tachycardia, Supraventricular tachycardia, Bullous rash, Alopecia.
Precautions of Idarubicin Hcl
Idarubicin is not recommended for use during pregnancy or lactation. It should be used with caution in patients with any pre-existing liver disease, kidney disease, heart disease, blood disorders or any allergy. Therapy should not be initiated until patient recover normal hematopoiesis after bone merrow depression. It should be used with caution in patient with dental diseases. IM injection should not be administered to the patients receiving idarubicin.