Magnesium Sulphate (Magnesium Sulphate)
Overview of Magnesium Sulphate
Magnesium Sulphate is a saline laxative. Magnesium Sulphate is used in constipation. It increases the bulk of intestinal contents and cause defecation. Magnesium Sulphate is also used to control seizures in pregnancy, to treat low magnesium levels, problems related to kidney conditions (nephritis) in children, to prevent premature contractions in pregnancy, to treat heart attack and asthma patients.
Indication of Magnesium Sulphate
Magnesium Sulphate is primarily indicated in conditions like Constipation, Convulsions, Eclampsia, Emergency treatment of serious arrhythmias, Hyperacidity, Hypomagnesaemia, Nephritis, Prevention of seizure recurrence in pre-eclampsia, Seizures, Suspected myocardial infarction, Symptomatic hypomagnesaemia, To prevent recurrence of defecits, and can also be given in adjunctive therapy as an alternative drug of choice in Premature labour.
Contraindication of Magnesium Sulphate
Magnesium Sulphate is contraindicated in conditions like Myocardial infarction,Heart block,Toxaemia of pregnancy,Renal impairment.
Side Effects of Magnesium Sulphate
The severe or irreversible adverse effects of Magnesium Sulphate, which give rise to further complications include Diarrhoea, Bradycardia, CNS depression, Hypocalcemia, Hypermanganesemia.,Magnesium Sulphate produces potentially life-threatening effects which include Coma, Cardiac Arrest, Cardiac arrest, Respiratory paralysis. which are responsible for the discontinuation of Magnesium Sulphate therapy.,The signs and symptoms that are produced after the acute overdosage of Magnesium Sulphate include Edema, Cardiac arrest.,The symptomatic adverse reactions produced by Magnesium Sulphate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Thirst, Drowsiness, Confusion, Hypotension, Flushing, Muscle weakness, Nausea and vomiting, Slurred speech, Respiratory depression, Confusion.
Precautions of Magnesium Sulphate
Do not exceed prescribed dose because it will cause diarrhea.Maintain urine output at level of 100ml every 4hrs.