Methenamine (Methenamine)
Overview of Methenamine
Methenamine used as a topical antiseptic and for urinary tract infections.
Indication of Methenamine
Methenamine is primarily indicated in conditions like Cytotoxic-induced neutropenia, Long-term treatment of healed gastro-oesophageal reflux disease, Urinary tract infection, and can also be given in adjunctive therapy as an alternative drug of choice in Drying secretions, amnesia.
Contraindication of Methenamine
Methenamine is contraindicated in conditions like Acidosis,Gout,Dehydration,Hepatic insufficiency.
Side Effects of Methenamine
The signs and symptoms that are produced after the acute overdosage of Methenamine include Diarrhea, Hematuria, Nausea & vomiting, Proteinuria, Inflamation of bladder, Painful micturition.,The symptomatic adverse reactions produced by Methenamine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Diarrhea, Pruritus, Skin RashX, Hypersensitivity, Nausea and vomiting.
Precautions of Methenamine
It should be used with caution in patients with dehydration, severe renal function impairment (as its salt may precipitate causing crystalluria), hypersensitivity to drug and hepatic function impairments.